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Poorly concentrated urine is associated with an increased risk of developing chronic kidney disease in apparently healthy cats.

Clinical evidence update from Journal of the American Veterinary Medical Association

Published Aug 31, 2026, 12:00 PM UTCStarted by Veterinary33 Editorial Desk0 repliesSep 9, 2026

Clinical Context

Peer-reviewed veterinary literature continues to shape everyday decision-making for feline patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.

What the Study Evaluated

A study published in Journal of the American Veterinary Medical Association in 2026 evaluated poorly concentrated urine is associated with an increased risk of developing chronic kidney disease in apparently healthy cats..

Key Findings

To evaluate medical records from mature and senior cats stratified by urine specific gravity (USG; ≥ 1.035 or < 1.035) to examine the development of presumptive chronic kidney disease (CKD). 15,027 apparently healthy cats were evaluated for inclusion in a 2-year longitudinal retrospective study. Outcome during the study period was a presumptive CKD diagnosis or development of creatinine…

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